However, most pharmaceutical-grade units have more uniform temperatures than household units under normal operating conditions.
Dating of multidose vials validating special characters
Combination refrigerator/freezer units are less capable of simultaneously maintaining proper storage temperatures in both compartments.
If a combination refrigerator/freezer must be used, only refrigerated vaccines should be stored in the unit, and a separate stand-alone freezer should be used for frozen vaccines.
Stand-alone units can vary in size from compact, under-the-counter (not dormitory) style to large, stand-alone, pharmaceutical grade units. Vaccines that are stored in the refrigerator portion of a combination refrigerator/freezer should be moved away from the vent located in the refrigerator compartment.
The cold air from the freezer is circulated into the refrigerator compartment to cool it, which can cause your vaccines to freeze.
In general, the unit must be large enough to store the year's largest vaccine inventory without crowding and to store water bottles (in a refrigerator) and frozen coolant packs (in a freezer) to stabilize the temperatures and minimize fluctuations.
Stand-alone units that only refrigerate or only freeze are recommended by CDC.
CDC recommends using separate refrigerator and freezer units for vaccine storage, but still allows use of a combination refrigerator/freezer if you only use the refrigerator portion for storing vaccines (as you are doing).
CDC also recommends that you store food and beverages in a separate storage unit from vaccines, which you are technically doing but there may still be an impact on the refrigerator temperature by the opening and closing of the freezer door by staff.
* Exception can be considered for multidose vials used for a single patient (e.g., allergy shots) if the manufacturer’s instructions state that the vial can be used for longer than 28 days.
The Centers for Disease Control and Prevention provides comprehensive information about vaccine storage and handling in their Storage and Handling Toolkit, available at gov/vaccines/hcp/admin/storage/toolkit/
CDC's Vaccine Storage and Handling Toolkit states that if other medications and biological products must be stored in the same unit as vaccines, never store these products in the same container with vaccines.